Maternal Exercise Uncovers Placental Insufficiency in Diabetic Mothers

Placental Insufficiency.

Transfer of Maternal Immunity to Newborns of Diabetic Mothers

This study was carried out with hyperglycemic pregnant women to investigate the transfer of antibody classes to newborns across the placenta or by colostrum and the functional activity of phagocytes in maternal blood, cord blood, and colostrum from diabetes mothers. Samples from maternal blood, cord blood, and colostrum were collected from 20 normoglycemic and 20 hyperglycemic pregnant women. W...

The histopathology of placental insufficiency.

Voltaire, regarded by some as a realist and by others as a cynic, remarked that 'if God did not exist it would be necessary to invent him'. One suspects that this comment is equally applicable to placental insufficiency, a concept that has similarly attracted not only faithful adherence but also bewildered agnosticism or defiant disbelief. Placental insufficiency has been largely defined in cli...

Maternal Choline Supplementation Alters Fetal Growth Patterns in a Mouse Model of Placental Insufficiency

Impairments in placental development can adversely affect pregnancy outcomes. The bioactive nutrient choline may mitigate some of these impairments, as suggested by data in humans, animals, and human trophoblasts. Herein, we investigated the effects of maternal choline supplementation (MCS) on parameters of fetal growth in a Dlx3+/- (distal-less homeobox 3) mouse model of placental insufficienc...

Examining Material Hardship in Mothers: Associations of Diaper Need and Food Insufficiency with Maternal Depressive Symptoms

Objectives: Material hardship represents a potential mechanism by which poverty influences the mental health of mothers. This study examined the association between two forms of material hardship, diaper need and food insufficiency, and maternal depressive symptoms. Methods: Data were from a cross-sectional study of 296 urban, pregnant or parenting, low-income women. A linear regression model w...